Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 26;29(2):458–466. doi: 10.1038/s41591-022-02181-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 7 — a, Pearson correlation (two-sided) of ISGs induction (average of log2FC of ISGs in Fig. 4a) and MAPK pathway inhibition (average of log2FC of DUSP6, ETV4, ETV5, and SPRY4) in DT-treated organoids. b, Log2FC of gene expression (measured by qPCR) of indicated ISGs in organoids (derived from patient 18) treated with DP for 72 hours (n = 3 independent biological experiments, data are presented as mean values +/− SEM). c, Indicated organoids were treated with various doses of DT or DE for 72 hours, and subjected to cell viability assay (n = 3, data are presented as mean values +/− SEM). d, Relative DUSP6 expression in organoid treated with various doses of DT or DE for 6 hours (n = 3, data are presented as mean values +/− SEM). e, ISGs induction in indicated organoids treated with two different doses of DT (n = 3, data are presented as mean values +/− SEM).