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. 2023 Jan 26;29(2):458–466. doi: 10.1038/s41591-022-02181-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — a, Best percent change from baseline over time per RECIST v1.1 criteria for patients in the total intention-to-treat cohort. b, Kaplan–Meier estimates of progression-free survival assessed according to RECIST v1.1 for patients in the total intention-to-treat cohort. c, Kaplan–Meier estimates of overall survival assessed according to RECIST v1.1 for patients in the total intention-to-treat cohort. d, Kaplan–Meier estimates of time on treatment assessed according to RECIST v1.1 for patients in the total intention-to-treat cohort. e, Kaplan-Meier estimates of progression-free survival assessed according to RECIST v1.1 for patients without prior receipt of a BRAF inhibitor and/or immunotherapy, and with microsatellite stability in the intention-to-treat cohort. f, difference in PFS by sidedness for patients in the total intention-to-treat cohort (Cox regression test). g, ORR, PFS, and OS information of patients with prior BRAFi or ICB.