Extended Data Table 3.

Subgroup analysis of antitumor response assessed by independent radiological review committee in the ITT population

Antitumor response was assessed per the Response Evaluation Criteria in Solid Tumors version 1.1. CF = cisplatin and 5-fluorouracil. CI = confidence interval. CPS = combined positive score. CR = complete response. PD-L1 = programmed death ligand 1. PR = partial response. SD = stable disease. *Objective response rate was defined as proportion of patients achieving complete or partial response. †Disease control rate was defined as proportion of patients achieving complete response, partial response, or stable disease. ‡Duration of response was assessed in patients who achieved complete or partial response and defined as time from first objective response to disease progression or death from any cause.