Table 2.
Summary of CVD events during follow-up according to four separate groups.
| Control | MCE | IS | ICH or SAH | |
|---|---|---|---|---|
| Number of events | ||||
| CVD cases | 451 | 807 | 3562 | 3342 |
| MCE cases | 86 | 803 | 143 | 97 |
| IS cases | 321 | 25 | 3547 | 601 |
| ICH or SAH cases | 74 | 2 | 213 | 3316 |
| Incidence, per 1000 person-years | ||||
| CVD cases | 9.8 | 201.7 | 194.8 | 227.3 |
| MCE cases | 1.9 | 200.2 | 3.5 | 3.8 |
| IS cases | 7.0 | 4.4 | 193.5 | 25.9 |
| ICH or SAH cases | 1.6 | 0.3 | 5.3 | 224.0 |
| Median (IQR) time to events, year | ||||
| Deaths/loss to follow-up/1 Jan 2018 | 11.6 (1.9) | 5.8 (7.4) | 11.0 (2.1) | 7.2 (7.1) |
| CVD cases | 11.5 (2.1) | 4.4 (3.9) | 4.6 (3.8) | 4.1 (3.6) |
| MCE | 11.6 (1.9) | 4.4 (3.9) | 11.0 (2.1) | 7.2 (7.1) |
| IS cases | 11.5 (2.0) | 5.8 (7.3) | 4.6 (3.8) | 6.2 (6.7) |
| ICH or SAH cases | 11.6 (1.9) | 5.8 (7.4) | 11.0 (2.1) | 4.1 (3.6) |
IQR: interquartile range; CVD: cardiovascular disease; MCE: major coronary event; IS: ischemic stroke; ICH: intracranial hemorrhage; SAH: subarachnoid hemorrhage.
CVD cases correspond to any first occurrence of MCE, IS (ICD10: I63, I69.3), ICH (I61, I69.1), or SAH (I60, I69.0) till the censoring date of 1 Jan 2018. MCE refers to nonfatal myocardial infarction (I21-23) or fatal IHD (I20-25) here.