Table 4.

Harrell's C-index and NRI for CA and KDM-AA models in all participants and four separate groups.

	Harrell's C-index (95% CI)		NRI (95% CI)
	Basic model + CA	Basic model + CA + KDM-AA
All	0.813 (0.807, 0.819)	0.821 (0.815, 0.826)	0.011 (0.003, 0.019)
Control	0.775 (0.758, 0.793)	0.794 (0.777, 0.811)	0.073 (0.048, 0.099)
MCE	0.641 (0.619, 0.664)	0.652 (0.629, 0.674)	0.019 (−0.020, 0.058)
IS	0.745 (0.726, 0.765)	0.765 (0.747, 0.784)	0.036 (0.008, 0.065)
ICH or SAH	0.665 (0.653, 0.677)	0.676 (0.664, 0.687)	0.021 (0.002, 0.040)

NRI: net reclassification index; CA: chronological age; KDM: Klemera and Doubal's method; CI: confidence interval; AA: age acceleration; MCE: major coronary event; IS: ischemic stroke; ICH: intracranial hemorrhage; SAH: subarachnoid hemorrhage.

Basic Cox models were adjusted for sex, fasting status, educational attainment, urban or rural areas, and lifestyle factors (smoking, alcohol drinking, dietary habits, physical activity level), stratified jointly by study areas and four groups.