Table 2.

Effects of AMPKα2 knockout on mouse left ventricular function and dimension in mice

Parameter	WT mice	AK mice
LVEF (%)	81.06 ± 6.99	69.93 ± 17.45
FS (%)	48.85 ± 8.26	40.08 ± 13.92
LVEDD (mm)	2.90 ± 0.09	3.18 ± 0.07
E/A	1.79 ± 0.25	0.68 ± 0.15a
E'/A'	1.55 ± 0.84	1.24 ± 0.07

Abbreviations: AK, AMPKα2 knockout; E/A, the ratio of the early to late diastolic mitral inflow velocities; E'/A', the ratio of the early to late diastolic mitral annular velocities; FS, fractional shortening; LVEDD, Left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction.

^ap < 0.05, n = 5 per group.