Table 1.

Interatrial shunt devices and key studies. RV, right ventricle; KCCQ, Kansas City Cardiomyopathy Questionnaire; PCWP, pulmonary capillary wedge pressure; 6MWD, 6-min walk distance

Devices	Key studies	Findings
Corvia interatrial shunt device	REDUCE-LAP HF I (NCT02600234) REDUCE-LAP HF II (NCT03088033)	Improved functional class Improved KCCQ score Reduction in PCWP
V-wave interatrial shunt device	RELIEVE-HF (NCT03499236)	Improved KCCQ score
Occlutech atrial flow regulator	PRELIEVE (NCT03030274)	Improved functional class Increased RV diameter Preserved RV function
Alleviant system	ALLEVIATE-HF-1 (NCT04583527)	Improved KCCQ Reduction in PCWP
NoYA RF-based interatrial shunt system		Increased 6MWD Improved functional class
Edwards LA-coronary sinus shunt	Alt FLOW US (NCT03523416)	Improved KCCQ score Reduction in PCWP