Fig. 2.

miR-576 promoted EC cells’ proliferation in vitro and in vivo. A Downregulation of miR-576 expression suppresses the proliferation of ishikawa and AN3-CA cells. Upregulation of miR-576 promotes the proliferation of EC cells. B Downregulation of miR-576 expression suppresses the colony formation of EC cells. Upregulation of miR-576 expression plays the opposite role. C The effect of miR-576 overexpression on tumorigenesis in vivo. (i) Overexpression of miR-576 promoted EC cell-derived tumor growth in a xenograft model. (ii) The tumor weight of overexpressed miR-576 was increased than that of NC