TABLE 1.

Inclusion/exclusion criteria for shortlisting of the compounds.

	Name	Criteria
1	Lipinski and other violations	Zero violations
2	Molecular weight (MW)	150–500
3	TPSA	20–130
4	GI absorption	High
5	BBB permeability	No
6	Medicinal chemistry violations	Zero violations
7	Water solubility	Soluble/very soluble
8	Cardiotoxicity (hERG prediction)	No
9	CYP450 inhibition	Non-inhibitor