Figure 2.
Graphical representation of marrow-derived stem cell (MSC) therapy for intervertebral disc (IVD) degeneration. MSCs are collected from bone marrow, amplified in vitro, and then cultured under various conditions to differentiate into nucleus pulposus (NP) cells. The differentiated cells are then seeded on a biomaterial or scaffold and the substitute is injected into the target IVD.