Figure 3.

Splanchnic nerve modulation

The splanchnic vascular compartment is a major a reservoir for intravascular blood volume and has an important role in volume redistribution in heart failure (A). Splanchnic nerves control the arterial and venous vascular tone of this vascular compartment; and therefore, splanchnic nerve block can be a potential treatment modality in heart failure (B). Fudim et al showed improvement in right atrial pressure, mean arterial pressure, pulmonary arterial mean pressure, and wedge pressure after a temporary block of the splanchnic nerve in patients with heart failure (C).