Table 4.
Lipophilic chemicals which were rated as false-positive vs guinea pig in the studies by Kreiling et al. and Ball et al.
| CAS | Structure | Name | cLogP Chem-Draw | LLNA Result (EC3%) | Guinea pig result |
|---|---|---|---|---|---|
| Study of Kreiling et al. | |||||
| 112-80-1 |  |
Oleic acid | 7.8 | 10.4 | negative |
| 60-33-3 |  |
Linoleic acid | 7.3 | 14 | negative/ambiguous |
| 463-40-1 |  |
Linolenic acid | 6.8 | 10 | negative |
| 111-02-4 |  |
Squalene | 12.9 | <10% | negative |
| Study of Ball et al. | |||||
| n.a. |  |
Hexadecan-1-ol, Ethoxylated (2 EO) | 7 | 1.2 | negative (0/20) |
| n.a. |  |
Decylphenolpolyethylene glycol ether | 4.8 | 2.0 | negative (0/20) |
| n.a. |  |
Hexaethylene glycol monododecyl ether | 4.2 | 7.4 | negative (0/20) |
| n.a. |  |
Tetraethylene glycol monotetradecyl ether | 5.6 | 2.8 | negative (0/20) |