Figure 4.

White matter (WM)/gray matter (GM) ratio, cored, and diffuse plaque (A), cored plaque (B) counts, and WM/GM ratio (C) for each case by preanalytic variable. Cases with none/low likelihood Alzheimer disease (AD) [5, 6, 8, 10, 11, 14] typically had low numbers of core plaques, while cases with high likelihood AD [1, 3, 4, 12, 13] had higher counts. More information on the demographics of cases located in Supplementary Data Table S2. Further details on case 6 for GM/WM ratio is located within Supplementary Data Fig. S4.