Table 2. Montgomery-Åsberg Depression Rating Scale Scores by Treatment Condition and Time Point.
| Variable | Baseline | Week 2 | Week 4 | Week 8 | Week 12 |
|---|---|---|---|---|---|
| Descriptive statistics | |||||
| Simvastatin | |||||
| No. of patients | 77 | 73 | 71 | 71 | 69 |
| Mean (SD) HamD-24 score | 28.0 (7.2) | 21.9 (9.2) | 20.3 (8.5) | 19.3 (10.2) | 15.5 (7.4) |
| Placebo | |||||
| No. of patients | 73 | 68 | 67 | 67 | 67 |
| Mean (SD) HamD-24 score | 29.5 (7.2) | 21.8 (10.2) | 20.4 (9.7) | 19.8 (9.4) | 17.2 (11.1) |
| Adjusted group difference | |||||
| Mean (95% CI) | NA | 0.71 (−2.32 to 3.74) | 0.57 (−2.49 to 3.62) | 0.13 (−2.92 to 3.19) | −0.61 (−3.69 to 2.46) |
| SES (95% CI) | NA | 0.1 (−0.32 to 0.52) | 0.08 (−0.34 to 0.5) | 0.02 (−0.4 to 0.44) | −0.08 (−0.51 to 0.34) |
| t (df) | NA | 0.5 (339.3) | 0.4 (343.8) | 0.1 (344) | −0.4 (348.7) |
| P value | NA | .65 | .72 | .93 | .70 |
Abbreviations: HamD-24, Hamilton Rating Scale for Depression; NA, not applicable; SES, standardized effect size.