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. 2023 Feb 6;25:e42864. doi: 10.2196/42864

Table 4.

Number of effect sizes showing effects (N=45).


Total number of effect sizes reported Human-supported interventions had significantly greater effects, n (%) No significant differences between human-supported and unsupported interventions, n (%) Unsupported interventions had significantly greater effects, n (%)
Outcome domains

Anxiety 12 4 (33) 7 (58) 1 (8)

Depression 19 9 (47) 8 (42) 2 (10)

PTSDa 2 1 (50) 1 (50) 0 (0)

Stress 3 2 (66) 0 (0) 1 (33)

Multiple 9 6 (66) 3 (33) 0 (0)
Sample characteristics

Clinical or subclinical 21 12 (57) 9 (42) 0 (0)


Anxiety disorders 1 1 (100) 0 (0) 0 (0)


Social anxiety 2 0 (0) 2 (100) 0 (0)


Depression 6 3 (50) 3 (50) 0 (0)


Anxiety disorders or depression 4 3 (75) 1 (25) 0 (0)


PTSD 3 1 (33) 2 (66) 0 (0)


Unrestricted mental health conditions 5 4 (80) 1 (20) 0 (0)

Unrestricted samples 24 10 (41) 10 (41) 4 (16)
Quality of RCTb

High 2 1 (50) 1 (50) 0 (0)

Medium 19 9 (47) 8 (42) 2 (10)

Low 24 12 (50) 10 (41) 2 (8)
Type of human support

Clinically trainedc 17 8 (47) 8 (47) 1 (5)

Mixedd 9 7 (77) 2 (22) 0 (0)

Uncleare 19 7 (36) 9 (47) 3 (15)

aPTSD: posttraumatic stress disorder.

bRCT: randomized controlled trial.

cClinically trained is defined as a therapist, clinical psychologist, or clinical psychology trainee.

dMixed support providers included both clinically trained individuals and individuals who did not have clinical training providing support for DMHIs.

eUnclear means that the authors did not provide information about the type of support provider in the meta-analysis.