Time response of significantly altered gene expression (mean ΔCT) following either leptin or adiponectin treatment. Results are plotted for four different time points (3, 6, 18, and 24 h), respectively. Error bars show standard deviations. Significant results at a certain time point compared to the respective control are marked with an asterisk. For leptin treatment (top panel ‘Leptin’), expression results of IL-8 and TNF-α are shown. For adiponectin treatment (bottom panel ‘Adiponectin’), expression results of CCL22, IL-8, CXCL10, IL-1β, and TNF-α are shown. Blue graphs = negative controls, Red graphs = treated cells, IL-8 = interleukin-8; TNF-α = tumor necrosis factor-alpha; CCL22 = C–C motif chemokine ligand 22; CXCL10 = C-X-C motif chemokine ligand 10; IL-1β = interleukin-1 beta. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)