Skip to main content
. 2023 Feb 21;6:205. doi: 10.1038/s42003-023-04566-y

Fig. 4. eIk1, eIk2 and Nek4 function is conserved in the human malaria parasite P. falciparum.

Fig. 4

a, b Parasitemia of synchronized P. falciparum 3D7 WT, ΔeIK2 (PF3D7_0107600), ΔeIK1 (PF3D7_1444500) and Δnek4 (PF3D7_0719200) parasites cultured in (a) MetS or MetD media and (b) IleS or IleD media. c, d Merozoite numbers per schizont in P. falciparum parasites cultured in (c) MetS or MetD media and (d) IleS or IleD media. a, b. Data represents the mean percentage of iRBCs. Parasitemia was performed in triplicate, averaged and repeated in n = 2 independent experiments. c, d Data is represented as box-whisker plot (10–90 percentile) of mean merozoite number per schizont ± SD (Mann-Whitney). Boxplots show the data of n = 2 independent experiments and for the following number of schizonts (N): wild-type, MetS, N = 57; MetD, N = 58; IleS, N = 37; IleD, N = 33; ΔeIK2, MetS, N = 26; MetD, N = 25; IleS, N = 37; IleD, N = 42; ΔeIK1, MetS, N = 35; MetD, N = 44; IleS, N = 41; IleD, N = 36; and Δnek4, MetS, N = 22; MetD, N = 20; IleS, N = 45; IleD, N = 28.