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Study design characteristics of the included studies (n = 70)
| Study design | n (%) | Follow-up | n (%) | Funding | n (%) | Multicentric | n (%) | Pilot Study | n (%) |
|---|---|---|---|---|---|---|---|---|---|
| RCTs | 44 (62.9) | Yesa | 39 (55.7) | Yes | 43 (61.4) | Yes | 17 (24.3) | Yes | 20 (28.6) |
| Pre-post Clinical Trial (no control group) | 22 (31.4) | No | 31 (42.3) | No | 27 (38.6) | No | 53 (75.7) | No | 50 (71.4) |
| Non-RCT | 4 (5.7) |
aFollow-up range: 1–36 months
