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. Author manuscript; available in PMC: 2023 Feb 21.
Published in final edited form as: Semin Immunopathol. 2022 May 3;44(5):697–707. doi: 10.1007/s00281-022-00945-5

Fig. 1. Inhibitory receptors on glioblastoma-infiltrating T cells.

Fig. 1

A. The PD-1 receptor inhibits early T cell signaling following binding to PD-L1 which can be expressed by glioma cells and myeloid cells. B. The CD161 receptor inhibits activation of CD8 and CD4 T cells following binding to its CLEC2D ligand expressed by glioma cells and myeloid cells