Skip to main content
. Author manuscript; available in PMC: 2023 Feb 21.
Published in final edited form as: Semin Immunopathol. 2022 May 3;44(5):697–707. doi: 10.1007/s00281-022-00945-5

Fig. 2. Targeting of a heterogeneous population of glioma cells by polyclonal T cells with multiple antigen specificities.

Fig. 2

Vaccines that target multiple antigens, including neoantigens and/or shared tumor antigens, can induce polyclonal T cell populations in lymph nodes. Such polyclonal T cell populations could deal with heterogeneous glioma cell populations by inhibiting the outgrowth of tumor cells that have down-regulated or lost expression of a single antigen