Table 2.

CSCs targeted CAR-T cells therapy in clinical trials

Trial	Solid Tumor	Phase	Enrollment	NCT Number	Current status
CD133 CAR-T	Advanced malignancies	I/II	20	NCT02541370	Completed
MUC1 CAR-T/PD-1 KO	Advanced esophageal cancer	I/II	20	NCT03706326	Recruiting
EGFR IL-12 CAR-T	Metastatic colorectal cancer	I	20	NCT03542799	Not yet recruiting
MESO CAR-T	Refractory–relapsed ovarian cancer	I/II	20	NCT03916679	Recruiting
MESO-19 CAR-T	Metastatic pancreatic cancer	I	4	NCT02465983	Completed
MOv19-BBz CAR -T	Recurrent high-grade serous ovarian cancer	I	18	NCT03585764	Recruiting
LeY CAR-T	Advanced cancer	I	30	NCT03851146	Recruiting
EpCAM CAR-T	Recurrent breast cancer	I	30	NCT02915445	Recruiting