Table 3.
Antibacterial activity of l-tyrosine against six MDR bacterial strains
Strains | Zone of inhibition (mm) ± standard deviation | MIC (µg/ml) | ||||
---|---|---|---|---|---|---|
Different concentrations of l-tyrosine (µg/ml) | ||||||
10 | 20 | 30 | 40 | 50 | ||
Gram-negative bacteria | ||||||
PA-02 | 9.0 ± 0.5 | 11 ± 0.7 | 19 ± 0.3 | 28 ± 1.1 | 31 ± 1.0 | 6 |
PA-09 | 8.0 ± 0.7 | 10 ± 1.0 | 17 ± 0.9 | 25 ± 0.9 | 28 ± 1.5 | 8 |
KP-01 | 0.0 ± 0.0 | 8 ± 0.9 | 10 ± 0.4 | 16 ± 0.8 | 19 ± 0.5 | 15 |
EC-03 | 8.0 ± 1.0 | 11 ± 0.9 | 15 ± 1.0 | 20 ± 0.8 | 24 ± 1.1 | 10 |
Gram-positive bacteria | ||||||
SA-03 | 0.0 ± 0.0 | 9.0 ± 1.0 | 10 ± 0.5 | 13 ± 1.0 | 18 ± 1.0 | 20 |
SA-04 | 0.0 ± 0.0 | 8.0 ± 0.8 | 11 ± 0.6 | 19 ± 1.1 | 21 ± 0.9 | 15 |
MIC: Minimum inhibitory concentration. DMSO (1%) was used as a negative control and had no effect against the tested bacteria