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. 2023 Feb 20;22:31. doi: 10.1186/s12934-023-02041-1

Table 3.

Antibacterial activity of l-tyrosine against six MDR bacterial strains

Strains Zone of inhibition (mm) ± standard deviation MIC (µg/ml)
Different concentrations of l-tyrosine (µg/ml)
10 20 30 40 50
Gram-negative bacteria
 PA-02 9.0 ± 0.5 11 ± 0.7 19 ± 0.3 28 ± 1.1 31 ± 1.0 6
 PA-09 8.0 ± 0.7 10 ± 1.0 17 ± 0.9 25 ± 0.9 28 ± 1.5 8
 KP-01 0.0 ± 0.0 8 ± 0.9 10 ± 0.4 16 ± 0.8 19 ± 0.5 15
 EC-03 8.0 ± 1.0 11 ± 0.9 15 ± 1.0 20 ± 0.8 24 ± 1.1 10
Gram-positive bacteria
 SA-03 0.0 ± 0.0 9.0 ± 1.0 10 ± 0.5 13 ± 1.0 18 ± 1.0 20
 SA-04 0.0 ± 0.0 8.0 ± 0.8 11 ± 0.6 19 ± 1.1 21 ± 0.9 15

MIC: Minimum inhibitory concentration. DMSO (1%) was used as a negative control and had no effect against the tested bacteria