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. 2023 Feb 7;14:1057780. doi: 10.3389/fpsyt.2023.1057780

TABLE 5.

Number of drugs prescribed to patients being treated for bipolar disorder, expressed as n (%).

Acute episode Maintenance period
Number of drugs Baseline (n = 204) 3 months (n = 173) 6 months (n = 153) 9 months (n = 147) 12 months (n = 149) χ2 P
1 6 (2.9) 25 (14.5) 20 (13.1) 26 (17.7) 34 (22.8) 33.047 0.000
2 71 (34.8) 76 (43.9) 74 (48.4) 69 (46.9) 55 (36.9) 10.199 0.037
3 74 (36.3) 51 (29.5) 37 (24.2) 35 (23.8) 39 (26.2) 9.498 0.050
4 46 (22.5) 11 (6.4) 12 (7.8) 10 (6.8) 14 (9.4) 35.410 0.000
≥ 5 7 (3.4) 10 (5.8) 10 (6.5) 7 (4.8) 7 (4.7) 2.097 0.718
Mean number (SD) 2.9 ± 0.9 2.5 ± 1.0 2.5 ± 1.0 2.3 ± 1.0 2.4 ± 1.1 45.168 0.000