Table 1.
Study [Ref] | Year | Country | Setting | T2DM Sample Size | Control Group(s) Size and Clinical Features | Age (Years, Mean and Range) | RDW, T2DM vs Control | p | Analyzer | Time | Temperature | Preservative | Transport |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adane3 | 2020 | Ethiopia | OP | 164 | 82, healthy | 50, NR | 44±3.6 vs 44.3±5.0 (SD) | 0.212 | Sysmex KX21N | NR | NR | K2EDTA | NR |
Alshehri4 | 2017 | Saudi Arabia | IP | 205 | 200, healthy | 45.5±5.5 | 14.57±3.1 vs 12.63±2.58 (CV) | 0.047 | Cell-Dyn Ruby | NR | NR | EDTA | NR |
Arkew1 | 2022 | Ethiopia | OP | 110 | 110, healthy | 43.13±9.43 | 14.20 ±1.03 vs 13.61 ±0.74 (CV) | <0.001 | UniCel DxH 800 | NR | NR | K2EDTA | NR |
Arkew5 | 2021 | Ethiopia | OP | 134 | 134, healthy | 43.08±9.30 | 14.00 (13.40–14.70) vs 13.50 (13.10–14.00) (CV) | <0.001 | UniCel DxH 800 | NR | NR | EDTA | NR |
Biadgo6 | 2016 | Ethiopia | OP | 148 | 148, healthy | 49.09±8.1 | 47.3±2.6 vs 45.2±3.0 (SD) | <0.001 | Sysmex KX-21N | NR | NR | EDTA | NR |
Jabeen7 | 2013 | Pakistan | OP | 170 | 92, healthy | 51.08±0.7 | 14.41±0.14 vs 13.69±0.16 (CV) | 0.001 | Horiba ABX | <2 hrs | NR | EDTA | NR |
Olana8 | 2019 | Ethiopia | OP | 70 | 70, healthy | 53.17±11.64 (M); 49.7±9.89 (F) | 14.28±1.862 vs 12.76±0.993 (CV, M); 14.04±1.397 vs 13.08±1.10 (CV, F) | 0.001 (M) 0.012 (F) | NR | NR | NR | EDTA | NR |
Abbreviations: ref, reference number; T2DM, type 2 diabetes mellitus; RDW, red blood cell distribution width; OP, outpatient; NR, not reported; SD, standard deviation; K2EDTA, potassium salt of EDTA (ethylene diamine tetra acetic acid); IP, inpatient; CV, coefficient of variation; EDTA, ethylene diamine tetra acetic acid; M, male; F, female.