Table 1.
Enriched kyoto encyclopedia of genes and pathways in the very early exposure to EE group.
| Term | p value | Benjamini-Hochberg adjusted p value | Term | p value | Benjamini-Hochberg adjusted p value |
|---|---|---|---|---|---|
| mmu04145:Phagosome | 3.88E-21 | 9.96E-19 | mmu05417:Lipid and atherosclerosis | 1.97E-07 | 2.81E-06 |
| mmu04610:Complement and coagulation cascades | 9.73E-14 | 1.25E-11 | mmu05330:Allograft rejection | 2.60E-07 | 3.52E-06 |
| mmu05152:Tuberculosis | 1.15E-12 | 9.83E-11 | mmu05169:Epstein–Barr virus infection | 7.12E-07 | 8.89E-06 |
| mmu05133:Pertussis | 1.54E-12 | 9.92E-11 | mmu05171:Coronavirus disease - COVID-19 | 7.27E-07 | 8.89E-06 |
| mmu05140:Leishmaniasis | 2.39E-12 | 1.07E-10 | mmu04621:NOD-like receptor signaling pathway | 2.07E-06 | 2.42E-05 |
| mmu05150:Staphylococcus aureus infection | 2.50E-12 | 1.07E-10 | mmu05320:Autoimmune thyroid disease | 3.91E-06 | 4.37E-05 |
| mmu04640:Hematopoietic cell lineage | 8.13E-11 | 2.99E-09 | mmu05322:Systemic lupus erythematosus | 5.23E-06 | 5.60E-05 |
| mmu05323:Rheumatoid arthritis | 1.51E-10 | 4.86E-09 | mmu04512:ECM-receptor interaction | 1.33E-05 | 1.37E-04 |
| mmu05164:Influenza A | 2.14E-09 | 6.10E-08 | mmu04662:B cell receptor signaling pathway | 2.78E-05 | 2.72E-04 |
| mmu04060:Cytokine-cytokine receptor interaction | 1.35E-08 | 3.46E-07 | mmu04974:Protein digestion and absorption | 2.86E-05 | 2.72E-04 |
| mmu05332:Graft-versus-host disease | 3.29E-08 | 7.46E-07 | mmu05132:Salmonella infection | 3.62E-05 | 3.32E-04 |
| mmu04061:Viral protein interaction with cytokine and cytokine receptor | 3.48E-08 | 7.46E-07 | mmu05134:Legionellosis | 5.35E-05 | 4.75E-04 |
| mmu05416:Viral myocarditis | 7.03E-08 | 1.39E-06 | mmu04062:Chemokine signaling pathway | 5.57E-05 | 4.78E-04 |
| mmu04620:Toll-like receptor signaling pathway | 7.68E-08 | 1.41E-06 | mmu05321:Inflammatory bowel disease | 6.19E-05 | 5.13E-04 |
| mmu04612:Antigen processing and presentation | 9.77E-08 | 1.67E-06 | mmu04210:Apoptosis | 1.01E-04 | 8.08E-04 |
| mmu04380:Osteoclast differentiation | 1.25E-07 | 2.00E-06 | mmu04672:Intestinal immune network for IgA production | 1.20E-04 | 9.36E-04 |
| mmu04940:Type I diabetes mellitus | 1.35E-07 | 2.05E-06 |
The apoptosis pathway is shown in bold. These pathways are statistically significant with a Benjamini-Hochberg p < 0.001 according to database for annotation, visualization and integrated discovery (DAVID) analysis.