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. 2023 Feb 2;8(1):e00558-22. doi: 10.1128/msphere.00558-22

FIG 6.

FIG 6

Cytokine and chemokine profiling in the lungs of MA10- and USA-WA1/2020-infected K18-hACE2 mice. The proinflammatory cytokine and chemokine response occurs more rapidly in the lung of K18-hACE2 mice infected with the MA10 strain compared to those infected with USA-WA1/2020 strain. Heatmap depicting the fold change of protein expression in the lung of infected mice at 2, 4, and 6 dpi compared to mock infected K18-hACE2 mice. Color scale depicts differences in fold expression. Cytokines and chemokines that are significantly upregulated compared to the mock are marked with an asterisk.