TABLE 4.
Variable | Hazard ratio | p-value |
---|---|---|
EVE | 1.10 (0.73–1.66) | 0.642 |
Estimated GFR at time of starting EVE | 1.00 (0.99–1.01) | 0.938 |
FVC % predicted at time of starting EVE | 0.99 (0.98–1.00) | 0.023 |
No CLAD | REF | |
BOS a | 4.30 (2.16–8.58) | <0.0001 |
RAS a | 2.36 (1.23–4.53) | 0.010 |
Mycophenolate | 0.62 (0.40–0.98) | 0.043 |
Abbreviations: BOS, bronchiolitis obliterans syndrome; CLAD, chronic lung allograft dysfunction; EVE, everolimus; FVC, forced vital capacity; GFR, glomerular filtrate rate; RAS, restrictive allograft syndrome.
Diagnosis of BOS or RAS pre or post starting EVE.