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. 2023 Feb 7;36:10581. doi: 10.3389/ti.2023.10581

TABLE 4.

Multivariate analysis—risk factors for mortality: Propensity matched pairs post conversion to everolimus.

Variable Hazard ratio p-value
EVE 1.10 (0.73–1.66) 0.642
Estimated GFR at time of starting EVE 1.00 (0.99–1.01) 0.938
FVC % predicted at time of starting EVE 0.99 (0.98–1.00) 0.023
No CLAD REF
BOS a 4.30 (2.16–8.58) <0.0001
RAS a 2.36 (1.23–4.53) 0.010
Mycophenolate 0.62 (0.40–0.98) 0.043

Abbreviations: BOS, bronchiolitis obliterans syndrome; CLAD, chronic lung allograft dysfunction; EVE, everolimus; FVC, forced vital capacity; GFR, glomerular filtrate rate; RAS, restrictive allograft syndrome.

a

Diagnosis of BOS or RAS pre or post starting EVE.