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EDN3 expression in cervical cancer cells treated with 5-Aza. (A) Expression levels of EDN3 in C-33A, SiHa and CaSki cells. (B) Methylation levels (average percentage of methylation across 4 CpG sites) of EDN3 in C-33A, SiHa and CaSki cells. (C) The mRNA expression of EDN3 in C-33A, SiHa and CaSki cells before and after treatment with 5 and 10 μM 5-Aza. Values are mean ± SD, N = 3; *P<0.05; **P<0.01; ***P<0.001.
