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Southern analysis of TE fragments in 5FOA-resistant XL280α mutants recovered from the lungs, kidneys, and brain of two mice 10 d post-infection. Each mutant had an independent Tcn12 mutation in the URA5 gene. Genomic DNA was digested with PvuII and probed for (A) Tcn12, (B) T1, or (C) Cnl1. The XL280α inoculum strain is shown for comparison. Arrows indicate new TE fragments and asterisks indicate TE fragment loss.
