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. 2023 Jan 17;120(4):e2212813120. doi: 10.1073/pnas.2212813120

Fig. 3.

Fig. 3.

HDAC7 is required for host defense in vivo. (A) Schematic representation of infection strategy. (B–E) Core body temperature (B) and cfu in peritoneal cavity (C), liver (D), and spleen (E) of C57BL/6J mice infected with EC958 in the presence or absence of TMP195. (F–I) Core body temperature (F) and cfu in peritoneal cavity (G), liver (H) and spleen (I) of Hdac7+/+ and Hdac7−/− mice infected with EC958. Data show median ± interquartile range of 10 mice per treatment group. Statistical significance was determined by two-way ANOVA (B and F) or unpaired nonparametric Mann–Whitney test (C–E and G–I) (*P < 0.05; **P < 0.01; ***P < 0.001).