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. 2023 Jan 9;324(2):C573–C587. doi: 10.1152/ajpcell.00520.2022

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Figure 3. — Functional profiling of S139 mutants. A and B: effect of S^3.36 (S139) point mutants on Ca²⁺ mobilization evoked by various concentrations of 5-hydroxytryptamine (5-HT; A) or (R)-praziquantel [(R)-PZQ; B]. C and D: effect of S^3.36 (S139) point mutants on bioluminescence resonance energy transfer (BRET) evoked by various concentrations of 5-HT (C) or (R)-PZQ (D). Data points represent mean ± SE from n = 3 independent assays, except for wild type (WT) in C and D (n = 4) and S139V (n = 2).