Table 1.
Total body weight and hind limb muscle, heart, and testis mass (mg) normalized by body weight (g) in male mice
| 13 wk | 12 to 13 mo | 2 y | ||||
|---|---|---|---|---|---|---|
| Control (n = 12) | fmARKO (n = 11) | Control (n = 4) | fmARKO (n = 3) | Control (n = 7) | fmARKO (n = 3) | |
| Total body weight (g) | 25.2 ± 0.7 | 24.3 ± 0.6 | 28.6 ± 1.1 | 32.2 ± 1.8 | 32.2 ± 0.4 | 32.4 ± 2.1 |
| Gastocnemius (mg/g) | 5.7 ± 0.1 | 5.8 ± 0.1 | 5.3 ± 0.1 | 4.5 ± 0.2** | 4.3 ± 0.1 | 3.7 ± 0.2** |
| Soleus (mg/g) | 0.35 ± 0.01 | 0.32 ± 0.01 | 0.30 ± 0.01 | 0.26 ± 0.01* | 0.26 ± 0.01 | 0.15 ± 0.03*** |
| EDL (mg/g) | 0.46 ± 0.03 | 0.44 ± 0.02 | 0.37 ± 0.02 | 0.32 ± 0.02 | 0.33 ± 0.02 | 0.26 ± 0.05 |
| Tibialis (mg/g) | 2.4 ± 0.1 | 2.3 ± 0.1 | 2.2 ± 0.1 | 1.8 ± 0.1** | 1.8 ± 0.1 | 1.5 ± 0.1* |
| Hearts (mg/g) | 5.8 ± 0.2 | 5.6 ± 0.1 | 5.9 ± 0.5 | 5.7 ± 0.2 | 5.1 ± 0.2 | 5.5 ± 0.5 |
| Testis (mg/g) | 3.7 ± 0.1 | 4.1 ± 0.1*** | 3.6 ± 0.2 | 3.0 ± 0.1** | 2.9 ± 0.1 | 2.7 ± 0.1 |
Data are expressed ± SE.
*P < 0.05, **P < 0.01, ***P < 0.001, fmARKO compared with control mice.
EDL, extensor digitorum longus.