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. 2023 Feb 21;18(2):e0281857. doi: 10.1371/journal.pone.0281857

Table 3. Factors associated with DBS coverage (mixed-effects logistic regression).

N N (%) with DBS Crude OR (95% CI) P Adj. OR (95% CI) p
Timepoint <0.001
6 months 537 401 (74.7) 1
12 months 493 414 (84.0) 1.95 (1.37–2.78)
24 months 445 369 (82.9) 1.68 (1.17–2.42)
Time since DBS availability <0.001 <0.001
≤9 months 191 111 (58.1) 1 1
10–18 months 735 613 (83.4) 4.07 (2.64–6.27) 3.05 (2.01–4.64)
>19 months 549 460 (83.8) 4.09 (2.61–6.41) 3.05 (1.97–4.71)
PWID 0.63 0.72
No 830 661 (79.6) 1 1
Yes 645 523 (81.1) 1.10 (0.74–1.64) 0.94 (0.66–1.34)
Gender 0.11
Male 1069 846 (79.1) 1
Female 406 338 (83.2) 1.45 (0.92–2.27)
Age at ART initiation (years) 0.51
≤29 481 384 (79.8) 1.14 (0.73–1.79)
30–39 638 504 (79.0) 1
40–59 296 244 (82.4) 1.36 (0.80–2.33)
≥50 60 52 (86.7) 1.93 (0.65–5.70)
Current WHO stage 0.031 <0.001
1–2 1398 1127 (80.6) 1 1
3 59 47 (79.7) 0.79 (0.34–1.82) 0.55 (0.24–1.24)
4 18 10 (55.6) 0.17 (0.04–0.64) 0.08 (0.02–0.31)
Current BMI level 0.39
<17.5 116 91 (78.4) 0.78 (0.40–1.54)
17.5–20.0 495 389 (78.6) 0.77 (0.53–1.14)
20.0–25.0 830 680 (81.9) 1
≥25.0 34 24 (70.6) 0.48 (0.15–1.51)
Rural care setting 0.11 0.025
No 592 490 (82.8) 1 1
Yes 883 694 (78.6) 0.72 (0.48–1.07) 0.64 (0.44–0.95)
Kinh ethnicity 0.74
No 866 703 (81.2) 1
Yes 530 417 (78.7) 0.85 (0.56–1.29)
Unknown 79 64 (81.0) 1.02 (0.42–2.50)
Late visit attendance by 7 days1 0.045 0.052
No 1286 1047 (81.4) 1 1
Yes 189 137 (72.5) 0.63 (0.40–0.99) 0.65 (0.42–1.00)
Self-reported non adherence2 0.64
No 1334 1069 (80.1) 1
yes 141 115 (81.6) 0.87 (0.49–1.56)
Province <0.001 <0.001
Lai Chau 135 119 (88.1) 0.20 (0.07–0.58) 0.24 (0.08–0.74)
Lao Cai 127 105 (82.7) 0.12 (0.04–0.35) 0.13 (0.04–0.39)
Phu Tho 202 196 (97.0) 1 1
Thai Nguyen 183 167 (91.3) 0.30 (0.10–0.87) 0.24 (0.08–0.73)
Thanh Hoa 609 405 (66.5) 0.04 (0.02–0.11) 0.04 (0.02–0.11)
Yen Bai 219 192 (87.7) 0.19 (0.07–0.53) 0.20 (0.07–0.58)

DBS: dried blood spot; OR: odds ratio; CI: confidence interval; PWID: people who inject drugs; ART: antiretroviral therapy; WHO: World Health Organization; BMI: body mass index

1Being late by at least seven days or more within the last 3 months preceding the evaluation time.

2Reporting having missed at least one dose of ART within the 4 days preceding the clinical visits on at least one occasion within the last 3 months preceding the evaluation time.