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. 2023 Feb 21;18(2):e0282015. doi: 10.1371/journal.pone.0282015

Table 3. Toxicities and feeding status according to SMM status.

Without low SMM (n = 55) Low SMM (n = 42) P-value
Mucositis* 0.41
    I/II 49 (89.1%) 35 (83.3%)
    III/IV 6 (10.9%) 7 (16.7%)
Dermatitis* 0.98
    I/II 51 (92.7%) 39 (92.9%)
    III/IV 4 (7.3%) 3 (7.1%)
Dysphagia* 0.11
    I/II 23 (41.8%) 11 (26.2%)
    III/IV 32 (58.2%) 31 (73.8%)
Dysphagia before treatment 0.01
    I/II 48 (87.3%) 27 (64.3%)
    III/IV 7 (12.7%) 15 (35.7%)
Weight loss during treatment 0.40
    <10% 45 (81.8%) 37 (88.1%)
    > = 10% 10 (18.2%) 5 (11.9%)
Feeding-tube prior treatment 0.46
    No 38(69.1%) 26(61.9%)
    Yes 17(30.9%) 16(38.1%)

SMM skeletal muscle mass; Significance p calculated by Pearson’s chi-squared test, Mucositis, Dermatitis, and Dysphagia grouped according to CTCAE v5.0 [22]

*highest CTCAE classification during treatment