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Overview of the biomimetic calcium phosphate/polyelectrolyte multilayer (bCaP/PEM) coating process. (A) Application of the various layers of the bCaP/PEM coating on the bone graft substitute (Col/HA) disks for mouse calvarial bone defect implantation. (B) Schematic cross-section of the coatings and growth factors tested in this study showing the location of growth factors on either side of the bCaP barrier layer.
