Table 4.
Haplotype frequencies in the case and control groups and risk of ESCC.
| Haplotype (LAMA1) | Case (freq) | Control (freq) | Chi2 | Or [95% CI] | p value |
|---|---|---|---|---|---|
| Ars62081531Ars621993Grs539713Grs566655Ars73938538Crs607230 | 38.73 (1.9%) | 63.18 (2.8%) | — | — | |
| Ars62081531Ars621993Grs539713Grs566655Crs73938538Crs607230 | 4.99 (0.2%) | 2.60 (0.1%) | — | — | |
| Ars62081531Ars621993Grs539713Trs566655Ars73938538Crs607230 | 2.33 (0.1%) | 4.12 (0.2%) | — | — | |
| Ars62081531Grs621993Ars539713Trs566655Ars73938538Crs607230 | 200.31 (10.0%) | 269.91 (11.9%) | 4.823 | 0.803 [0.660∼0.977] | 0.028 |
| Ars62081531Grs621993Ars539713Trs566655Crs73938538Crs607230 | 13.40 (0.7%) | 15.93 (0.7%) | — | — | |
| Ars62081531Grs621993Grs539713Trs566655Ars73938538Crs607230 | 38.33 (1.9%) | 56.03 (2.5%) | — | — | |
| Grs62081531Ars621993Ars539713Grs566655Ars73938538Crs607230 | 7.10 (0.4%) | 4.11 (0.2%) | — | — | |
| Grs62081531Ars621993Ars539713Trs566655Ars73938538Crs607230 | 1.29 (0.1%) | 3.52 (0.2%) | — | — | |
| Grs62081531Ars621993Grs539713Grs566655Ars73938538Crs607230 | 168.31 (8.4%) | 171.67 (7.6%) | 0.731 | 1.102 [0.881∼1.379] | 0.393 |
| Grs62081531Ars621993Grs539713Grs566655Ars73938538Trs607230 | 18.19 (0.9%) | 30.69 (1.4%) | — | — | |
| Grs62081531Ars621993Grs539713Grs566655Crs73938538Crs607230 | 29.83 (1.5%) | 39.59 (1.7%) | — | — | |
| Grs62081531Ars621993Grs539713Grs566655Crs73938538Trs607230 | 3.90 (0.2%) | 7.69 (0.3%) | — | — | |
| Grs62081531Ars621993Grs539713Trs566655Ars73938538Crs607230 | 29.88 (1.5%) | 35.63 (1.6%) | — | — | |
| Grs62081531Ars621993Grs539713Trs566655Ars73938538Trs607230 | 12.55 (0.6%) | 18.16 (0.8%) | — | — | |
| Grs62081531Ars621993Grs539713Trs566655Crs73938538Crs607230 | 6.78 (0.3%) | 3.95 (0.2%) | — | — | |
| Grs62081531Grs621993Ars539713Trs566655Ars73938538Crs607230 | 845.42 (42.2%) | 909.38 (40.1%) | 1.066 | 1.072 [0.939∼1.224] | 0.302 |
| Grs62081531Grs621993Ars539713Trs566655Ars73938538Trs607230 | 259.49 (12.9%) | 275 (11.9%) | 0.720 | 1.083 [0.900∼1.303] | 0.396 |
| Grs62081531Grs621993Ars539713Trs566655Crs73938538Crs607230 | 74.63 (3.7%) | 119.97 (5.3%) | 6.626 | 0.679 [0.504∼0.913] | 0.010 |
| Grs62081531Grs621993Ars539713Trs566655Crs73938538Trs607230 | 40.47 (2.0%) | 43.28 (1.9%) | — | — | |
| Grs62081531Grs621993Grs539713Trs566655Ars73938538Crs607230 | 117.31 (5.9%) | 114.20 (5.0%) | 1.127 | 1.155 [0.885∼1.508] | 0.288 |
| Grs62081531Grs621993Grs539713Trs566655Ars73938538Trs607230 | 34.02 (1.7%) | 59.00 (2.6%) | — | — | |
| Grs62081531Grs621993Grs539713Trs566655Crs73938538Crs607230 | 8.56 (0.4%) | 15.83 (0.7%) | — | — |
Freq: frequency; OR: odds ratio; CI: confidence interval; p < 0.05 is regarded as statistically significant value.