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. 2022 Dec 30;110(2):215–227. doi: 10.1016/j.ajhg.2022.12.007

Figure 1.

Figure 1

Observed variation along the length of ZMYM3

The 1,370 aa ZMYM3 (Q14202, GenBank: NP_005087.1) is annotated with MYM-type zinc fingers (1–9, orange) and Cre-like domain (blue) as described by UniProt and InterPro.

(A) Hemizygous variants observed in males in this study are noted above the protein model, with de novo variants in red. aNote that p.Arg441Gln was observed in three unrelated males. Hemizygous variants that were previously reported in males are shown below the protein.10,25

(B) Maternally inherited (black) or de novo (red) heterozygous variants observed in females in this study are noted above the protein model.