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. 2023 Jan 6;110(2):326–335. doi: 10.1016/j.ajhg.2022.12.010

Figure 2.

Figure 2

Accuracy when increasing reference panel size for simulated sequence data with three-way admixture

The y axis shows squared correlation between true and inferred local ancestry dose averaged over ancestries and across four replicate simulations (details in subjects and methods). Error bars (±2 standard errors) are shown as gray lines. Each of the three ancestries is represented by a reference panel of size shown on the x axis, and each analysis includes 100 admixed individuals. MOSAIC could not analyze the data with 1,000 or more individuals per reference panel within the available 384 GB of computer memory. RFMix could not analyze the data with 10,000 individuals per reference panel within the allotted two days.