11. Dyslipidaemia ‐ Studies undertaking multivariable regression analyses to determine the effect of dyslipidaemia on progression to PDR.

Study	Study type	Time years	N at baseline	Adjustment factors	Effect estimate			P value	Comments
					Type	Value	95% CI
Type 1 and 2 diabetes
Harris 2013	Electronic database	5	4617	HbA1c, age, sex, race, comorbidities, medications	HR	0.83	0.47 to 1.47		Presence of dyslipidaemia
Jeng 2016	Electronic database	5	53,453	Age, gender, hypertension, diabetic nephropathy, comorbidities, medications	HR	0.86	0.71 to 1.03		Presence of dyslipidaemia

BMI: body mass index; CI: confidence interval; DBP: diastolic blood pressure; DM: diabetes mellitus; DR: diabetic retinopathy; HbA1c: glycated haemoglobin/haemoglobin A1c; HR: hazard ratio; NPDR: non‐proliferative diabetic retinopathy; OR: odds ratio; PDR: proliferative diabetic retinopathy; RR: risk ratio; SBP: systolic blood pressure; vs: versus