13. Triglycerides ‐ Studies undertaking multivariable regression analyses to determine the effect of triglycerides on progression to PDR.
| Study | Study type | Time years | N at baseline | Adjustment factors | Effect estimate | P value | Comments | ||
| Type | Value | 95% CI | |||||||
| Type 1 | |||||||||
| Porta 2001 | Prospective cohort | 7 | 2013 | HbA1c, DM duration | Reported narratively as nonsignificant | ||||
| Skrivarhaug 2006 | Prospective cohort | 24 | 368 | HbA1c, DM duration, DR severity at baseline, age, age DM diagnosis, sex, smoking status, hypertension, cholesterol, albumin excretion rate | RR | 1.55 | 1.06 to 1.95 | 0.02 | With increasing triglyceride level |
| Type 2 diabetes | |||||||||
| Lee 2021 | Retrospective cohort | 6 | 2623 | HbA1c, DR severity at baseline, age, sex, BMI | HR | 1.01 | 0.91 to 1.12 | 0.88 | Per one standard deviation |
BMI: body mass index; CI: confidence interval; DBP: diastolic blood pressure; DM: diabetes mellitus; DR: diabetic retinopathy; HbA1c: glycated haemoglobin/haemoglobin A1c; HR: hazard ratio; NPDR: non‐proliferative diabetic retinopathy; OR: odds ratio; PDR: proliferative diabetic retinopathy; RR: risk ratio; SBP: systolic blood pressure; vs: versus