Table 2.
Clinical outcomes among HCV/HIV-coinfected patients with and without baseline cirrhosis.
| Clinical outcomes | Patients | Person-years | Incidence per 1000 person-years (95% CI) | 5-year cumulative incidence (%) | 10-year cumulative incidence (%) |
| Hepatic events | 43 | 5073 | 8.5 (6.0–11.0) | 4.2 | 9.3 |
| Cirrhosis decompensation | 35 | 5065 | 6.9 (4.6–9.2) | 3.5 | 6.6 |
| SBP | 26 | – | – | – | – |
| Variceal bleeding | 16 | – | – | – | – |
| Hepatic encephalopathy | 8 | – | – | – | – |
| Hepatorenal syndrome | 4 | – | – | – | – |
| HCC | 13 | 5098 | 2.6 (1.2–3.9) | 1.2 | 3.5 |
| Liver-related mortality | 14 | 5112 | 2.7 (1.3–4.2) | 1.1 | 3.1 |
| Incident cirrhosis | 84/605∗ | 3932 | 21.4 (16.8–25.9) | 7.9 | 18.0 |
| All-cause mortality | 64 | 5123 | 12.5 (9.5–15.5) | 6.5 | 10.8 |
The CI is determined by assuming that the ratio conforms to the normal distribution.
∗
The 605 patients without baseline cirrhosis.
CI: Confidence interval; HCC: Hepatocellular carcinoma; HCV: Hepatitis C virus; HIV: Human immunodeficiency virus; SBP: Spontaneous bacterial peritonitis.