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. Author manuscript; available in PMC: 2023 Aug 3.
Published in final edited form as: Eur Respir J. 2022 Sep 7;60(3):2101032. doi: 10.1183/13993003.01032-2021

FIGURE 1.

FIGURE 1

Pseudomonas aeruginosa converts to a chronic infection in 6-month-old cystic fibrosis transmembrane conductance receptor knockout (KO) rats. Wild type (WT) and KO rats were infected with P. aeruginosa at both 2 and 6 months of age. CFUs recovered from lung homogenates at indicated time points after infection in a) 2-month-old and b) 6-month-old rats. Percentage weight change from day 0 in c) 2-month-old and d) 6-month-old rats following infection. Data are presented as mean±sem and analysed via two-way ANOVA with Sidak post-test. *: p<0.05, **: p<0.01, ***: p<0.001, ****: p<0.0001. n=6–8 per group.