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. Author manuscript; available in PMC: 2023 Aug 3.
Published before final editing as: Eur Respir J. 2022 Feb 3:2101032. doi: 10.1183/13993003.01032-2021

FIGURE 3.

FIGURE 3

Resolution of inflammatory response to Pseudomonas aeruginosa infection is impaired in 6-month-old cystic fibrosis transmembrane conductance receptor knockout (KO) rats. Representative haematoxylin and eosin images are shown from 0, 3, 7, 14 and 28 days post-infection in a) 2-month-old wild-type (WT) and KO rats and b) 6-month-old WT and KO rats. Morphometric analysis of the slides yielded area of each individual induced bronchus-associated lymph tissue (iBALT) per lung section in c) 2-month-old WT and KO rats and d) 6-month-old WT and KO rats. Data are presented as mean±sem and analysed via two-way ANOVA with Sidak post-test. ****: p<0.0001. n=6–8 per group. Scale bars=200 μm.