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. Author manuscript; available in PMC: 2023 Aug 3.
Published before final editing as: Eur Respir J. 2022 Feb 3:2101032. doi: 10.1183/13993003.01032-2021

FIGURE 8.

FIGURE 8

A second exposure following infection with Pseudomonas aeruginosa is poorly tolerated in 6-month-old cystic fibrosis transmembrane conductance receptor knockout (KO) rats. 6-month-old wild-type (WT) and KO rats infected with P. aeruginosa at day 0 were re-inoculated with the same strain at day 28. a) Lung homogenates were plated for CFU counts; data were analysed via one-way ANOVA with Tukey’s post-test. b) Weights were collected in both groups, and percentage change from baseline calculated; data were analysed via two-way ANOVA. c) Percentage of neutrophils in the bronchoalveolar lavage fluid were calculated; data between each genotype were analysed by a two-tailed t-test. ns: nonsignificant. *: p<0.05, **: p<0.01. n=5–6 per group.