. 2022 Oct 14;228(2):433–447. doi: 10.1007/s00429-022-02582-y

Table 3.

Local maxima of early (1–3 s) vs. late (4–14 s) thalamic responses to stimulation: cluster sizes, MNI coordinates and cluster level tests using threshold-free cluster enhancement (TFCE)

Stimulation, change Side	Cluster size (n voxels)	x	y	z	TFCE	p_FWE^a	TNA	OTCA
Light touch, early > late
Left	239	10	− 20	8	361.942	0.001	Right CL	PFC
		8	− 2	6	264.139	0.003	Right A	PFC
	82	− 8	− 6	6	209.347	0.007	Left A	PFC
		− 8	− 16	10	186.919	0.011	Left MD	PFC
	8	16	− 20	2	156.542	0.021	Right VLV	PreMC
Right						n.s.
Light touch, late > early
Left						n.s.
Right						n.s.
Galvanic, early > late
Left	830	14	− 14	8	856.675	0.001	Right VA	PFC
		6	− 2	6	719.046	0.001	Right A	TC
		14	− 10	16	715.389	0.001	Right VA	PFC
		6	− 8	10	686.752	0.001	Right A	TC
		− 6	− 12	14	658.412	0.002	Left VA	TC
		− 6	− 18	8	624.655	0.002	Left MD	PFC
Right	106	14	− 16	0	392.678	0.010	Right VLV	PreMC
		12	− 8	8	336.370	0.018	Right VA	PFC
		14	− 14	12	336.090	0.018	Right VA	PFC
		14	− 6	14	335.359	0.018	Right VA	PFC
		12	− 22	12	325.537	0.020	Right VLD	PFC
		8	− 2	4	317.749	0.022	Right A	PFC
	4	− 12	− 16	4	311.298	0.024	Left MD	PFC
	3	− 10	− 16	14	312.987	0.024	Left VA	PFC
Galvanic, late > early
Left						n.s
Right						n.s
Heat pain, early > late
Left						n.s
Right						n.s
Heat pain, late > early
Left						n.s
Right						n.s
Mechanical pain, early > late
Left	187	12	− 12	10	289.442	0.001	Right VA	PFC
		8	− 4	4	270.442	0.001	Right A	PFC
		6	− 6	− 6	142.883	0.016	–	–
Right						n.s
Mechanical pain, late > early
Left						n.s
Right						n.s

TNA thalamic nuclei atlas, A anterior, CL central-lateral/lateral-posterior/medial-pulvinar, MD medio-dorsal, P pulvinar, VA ventral-anterior, VLD ventral-latero-dorsal, VLV ventral-latero-ventral, OTCA oxford thalamic connectivity atlas, OC occipital cortex, PFC pre-frontal cortex, PPC posterior parietal cortex, PreMC pre-motor cortex, PriMC primary motor cortex, SC sensory cortex, TC temporal cortex

^aAs two tests are performed for each stimulus type and time frame (two stimulation sides) the significance threshold according to Bonferroni is set to α = 0.025