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. Author manuscript; available in PMC: 2023 Feb 22.
Published in final edited form as: Nat Biomed Eng. 2022 Aug 15;6(9):1017–1030. doi: 10.1038/s41551-022-00913-2

Fig. 2 |. Three-layer-model reconstruction algorithm and phantom-validation experiments.

Fig. 2 |

a, Three-layer-model initialization and reconstruction procedures. b, Tissue-simulating-phantom experiment for validating the accuracy and depth sensitivity of the optical properties. A translation stage moves the source fibre across the phantom for measurements at SDSs ranging from 6.2 cm to 10 cm. Nonlinear semi-infinite fitting is performed to reconstruct phantom absorption and scattering coefficients λ=830 nm. c, Schematic of a two-layer phantom experiment.