Phylogenetic distribution of encapsulins. (a) Phylogenetic tree based on 108 of the major bacterial and archaeal phyla (147). Encapsulin-containing phyla are highlighted in blue. Different encapsulin families present in any given phylum are shown with differently colored dots, as detailed in the key. (b) A list of encapsulin-containing phyla. Values in the Count column give the number of identified encapsulin operons and the total number of proteomes available in UniProt for any given phylum (number of identified systems/number of UniProt proteomes). Phyla colored red indicate new, uncultured, or unclassified organisms not shown in the phylogenetic tree. [Ca. Modulibacteria has been proposed as a CP but is not annotated as such in UniProt (148).] Abbreviations: CP, candidate phylum; Ca., Candidatus; UniProt, Universal Protein Resource.