Table 3.

Performance characteristics of sepsis score across cohorts for predicting 28-day mortality stratified by site

Model	Takeo, Cambodia C-statistic (95% CI)	P value	Durham, USA C-statistic (95% CI)	P value	Kumasi, Ghana C-statistic (95% CI)	P value
Age and Sex	0.68 (0.59 to 0.78)	–	0.68 (0.54 to 0.81)	–	0.57 (0.49 to 0.64)	–
MEWS	0.68 (0.59 to 0.78)	0.2102	0.68 (0.57 to 0.79)	0.4991	0.63 (0.56 to 0.70)	0.0097
NEWS	0.73 (0.63 to 0.83)	0.0106	0.71 (0.59 to 0.84)	0.2557	0.64 (0.57 to 0.70)	0.0022
qSOFA	0.68 (0.59 to 0.77)	0.5101	0.71 (0.54 to 0.89)	0.0365	0.72 (0.64 to 0.79)	<0.001*
SIRS	0.69 (0.60 to 0.78)	0.5020	0.69 (0.55 to 0.83)	0.5831	0.58 (0.51 to 0.65)	0.1882
UVA	0.71 (0.60 to 0.83)	0.0109	0.70 (0.55 to 0.85)	0.4753	0.77 (0.71 to 0.83)	<0.001*

P value are from Wald test of the adjusted Cox regression model. Each model is adjusted for age and sex.

*Significant at p<0.002.

MEWS, Modified Early Warning Score; NEWS, National Early Warning Score; qSOFA, quick Sequential Organ Failure Assessment; SIRS, Systemic Inflammatory Response Syndrome; UVA, Universal Vital Assessment.