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. 2022 Dec 15;14(2):e00558. doi: 10.14309/ctg.0000000000000558

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© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology

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Figure 2. — (a) Clinical high-resolution anoscopy (HRA) image of the right lateral squamocolumnar junction in the anal canal with (1) normal-appearing anal mucosa and (2) a distinct posterior anal canal lesion. Outlines indicate lesion boundaries and arrows denote the sites imaged with high-resolution microendoscopy (HRME) and biopsied. (b) HRME image of site 1, which was classified as negative by the multitask deep learning network (MTN) and HRA impression, and was determined to be anal intraepithelial neoplasia grade 1 (AIN 1) by histopathology. (c) HRME image of site 2, which was classified as positive by the MTN and HRA impression, and was determined to be anal intraepithelial neoplasia grade 2 (AIN 2) by histopathology. The contrast of the HRA image was improved through dynamic range adjustment.