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. 2022 Aug 25;37(2):871–880. doi: 10.1007/s00464-022-09459-5

Table 1.

The clinicopathological characteristics of pT1b ESCC between ER + SR and ER-alone groups

ER + SR ER-alone p value
(χ2 test)
(n = 42) (n = 124)
Age
Median [IQR] 60.5 [55.00, 64.00] 62 [57.00, 67.00] 0.101#
Sex
Female 5 (11.9%) 31 (25.0%) 0.118
Male 37 (88.1%) 93 (75.0%)
SMI ≥ 200 μm
Negative 5 (11.9%) 33 (26.6%) 0.080
Positive 37 (88.1%) 91 (73.4%)
VM
Negative 32 (76.2%) 121 (97.6%)  < 0.001^
Positive 10 (23.8%) 3 (2.4%)
LVI
Negative 29 (69.0%) 108 (87.1%) 0.015
Positive 13 (31.0%) 16 (12.9%)
PD
Negative 30 (71.4%) 72 (58.1%) 0.176
Positive 12 (28.6%) 52 (41.9%)
Location
Upper 7 (16.7%) 17 (13.7%) 0.319
Middle 9 (21.4%) 42 (33.9%)
Lower 26 (61.9%) 65 (52.4%)
Concurrent LNM
Negative 32 (76.2%) NA NA
Positive 10 (23.8%) NA
Post-resection LNM
Negative 40 (97.6%) 119 (96.0%) 1.000^
Positive 1 (2.4%)a 5 (4.0%)
Overall LNM
Negative 32 (76.2%) 119 (96.0%)  < 0.001
Positive 10 (23.8%) 5 (4.0%)
Post-resection DOM
Negative 36 (87.8%) 117 (94.4%) 0.292
Positive 5 (12.2%) 7 (5.6%)

IQR interquartile range; PD poor differentiation; LVI lymphovascular invasion; VM vertical margin; SMI Submucosal invasion; LNM lymph node metastasis; DOM distant organ metastasis; NA not available

#Mann–Whitney test

^Fisher’s exact test

aOne case with ER + SR treatment revealed both concurrent and post-resection LNM